MI-SIM Pro+ with SYNER

Super-Resolution Imaging Super-Resolution Imaging

MI-SIM Pro+ with SYNER combines the advanced imaging capabilities of the MI-SIM platform with the optional SYNER dual-camera module. The system supports high-speed sequential or simultaneous acquisition of two fluorescence channels, making it particularly suitable for studying fast interactions between multiple cellular structures.

Unlike conventional dual-camera systems limited to two fixed channels, SYNER uses dual filter wheels and motorised dichroic switching to support flexible multi-channel experiments with more than four fluorescence channels.

Features

Resolution down to 60 nm in X–Y and 200 nm in Z
2D, 3D and TIRF structured illumination microscopy
SYNER dual-camera imaging module
Sequential or simultaneous dual-channel SIM acquisition
Support for experiments with more than four fluorescence channels
Dual filter wheels and motorised dichroic switching
Single-camera bypass mode for flexible acquisition
Digital image alignment tools for consistent channel registration
Real-time super-resolution reconstruction and preview
Multi-position, tracking and event-triggered imaging
Low photo-stress imaging for long-term live-cell studies
Integrated Imager and FINER software

Technology

Super-Resolution Imaging

Super-resolution imaging includes advanced microscopy techniques that overcome the diffraction limit of conventional light microscopy. While standard optical microscopes typically cannot distinguish structures closer than approximately 200 nm, super-resolut...
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