Cell Xpanse

Super-Resolution Imaging Super-Resolution Imaging

Cell Xpanse is a versatile multimodal imaging platform combining MI-SIM super-resolution microscopy with high-throughput spinning-disk confocal imaging. It enables researchers to move from the rapid exploration of large-format or three-dimensional samples to detailed subcellular imaging within a single integrated system.

By combining spinning-disk confocal, SPIN-SACD and SIM technologies, Cell Xpanse provides different levels of resolution, imaging depth and acquisition speed. This makes it suitable for samples ranging from bacteria and living cells to tissue sections, organoids and model organisms.

Features

Integrated MI-SIM and spinning-disk confocal microscopy
2D, 3D and TIRF-SIM imaging modes
SPIN-SACD super-resolution imaging
SPIN-SACD resolution down to 120 nm
Fast and sensitive imaging of thick, three-dimensional samples
High-throughput multi-site imaging
Large-area sample overview and detailed subcellular imaging
Advanced deconvolution and AI denoising
Reduced pinhole cross-talk in spinning-disk images
Event-based AI triggering
Automated adjustment of imaging settings following detected events
3D visualisation and batch image processing
Suitable for dynamic live samples and complex multi-protein experiments

Technology

Super-Resolution Imaging

Super-resolution imaging includes advanced microscopy techniques that overcome the diffraction limit of conventional light microscopy. While standard optical microscopes typically cannot distinguish structures closer than approximately 200 nm, super-resolut...
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