DropletONE

DropletONE is a fully integrated microfluidic system that combines droplet generation, real-time high-speed imaging, intelligent analysis, and precise sorting in one compact device. Designed for streamlined workflows, it produces consistent, label-free droplets with dynamic feedback control and advanced visual analytics, enabling high-throughput experiments in single-cell genomics, drug discovery, microbiology, and more. Powered by intuitive software and versatile compatibility, DropletONE empowers researchers with unmatched control, speed, and reproducibility for demanding life-science applications.

Features

Sorting Method	Active Dielectrophoretic
Sorting Efficiency, Selectivity, Purity	Up to 99 % demonstrated
Droplet Sizes	10 µm to 1 mm diameter
Detection Methods	Bright field image
Detection Parameters	Brightness/intensity; brightness contrast; circumference; area; surface roughness; colocalization; particle count; area contrast; fill factor; elongation; circularity; size; velocity; position; granularity; removal of small dirt particles; area of no contrast; contrast within particles; particles touching walls; particles touching image boundaries; particle position; particle velocity
Quality Control	In-line, multispectral image per particle pre & post sorting; all droplets recorded
Sample Viability	Further downstream usage of the sample; maximized cell viability
Assay-based Sorting	Yes

Applications

Droplet Generation, Manipulation, Analysis & Sorting
(Singel) Cell Sorting
(Single) Cell Analysis
Cell Therapy
Cell Line Development
Drug Discovery
Antibody Discovery
Drop-Seq
(RNA / DNA) Sequencing
Particle Synthesis, Analysis & Sorting
Bacteria Analysis & Sorting
Algae Analysis & Sorting
Yeast Analysis & Sorting
Sperm Analysis & Sorting
Organoid Generation, Screening & Sorting

Download the full DropletONE Specifications in Documents.

Specifications

Droplet Generation	Precise generation and control of droplets via feedback-loop
Flow Control	Adjustable flow rates ranging from µL/min to mL/min, offering flexible options for various experimental needs.
Droplet Parameters	Supports droplet diameters from tens to hundreds of micrometers, with tunable size and generation frequency.
Imaging Sensor	High-performance camera with integrated analysis and feature extraction
Frame Rate	210 fps @ 1280×1024 px, up to 10000 fps @ 400×32 px, monochrome, 10bit color depth
Sensitivity	Wavelength range 300-1000 nm, 58% QE @ 550nm peak ; 62% QE @ 630nm; global shutter
Readout Regions	2 freely selectable, simultaneous readout regions, e.g. for two stage processes, immediate quality control or parallelization.
Latency	Image capture and analysis latency is under 200 microseconds, enabling real-time responsiveness.
Illumination Unit	Single-color pulsed illumination (0.1–5 µs flash duration) delivers ultra-sharp imaging, eliminating motion blur and minimizing photodegradation in sensitive samples.
Software	User-friendly and feature-rich graphical user-interface for observation, analysis, and control
Analysis	Real-time analysis of various detection parameters like size, velocity, position, granularity, circumference etc.
Gating	Freely configurable gating; graphical marking in scatter plot; arbitrary points polygon
Triggers	Freely programmable and independent triggers; latency down to 200µs (frame rate dependent)
Storage Format	RAW; AVI uncompressed; MJPEG; MP4; XLS; XLSX; CSV (infinite recording)
Size & Weight	Compact all-in-one system that easily fits into every lab
Dimensions (L×W×H/mm)	428×380×322
Weight	25 kg