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geneMAP™ FXIII Mutation Detection Kit

geneMAP™ FXIII Mutation Detection Kit

Genmark

The geneMAP™ FXIII Mutation Detection Kit is a fast and accurate real-time PCR test for the detection of a G>T transition in exon 2 of the human coagulation Factor XIII (F13A) gene. This polymorphism leads to a valine (V) to leucine (L) substitution at amino acid 34 of the FXIII subunit A. The L variant has been described as having a small but significant protective effect against both arterial and venous thrombosis. The kit is designed to identify carriers of the V34L variant among at-risk patients of hereditary thrombophilia.

Size: 50 tests

Features

  • Easy to use with a ready-to-use reaction mix.
  • Delivers accurate results, including Homozygous and Heterozygous controls.
  • Compatible with dual-color real-time PCR instruments using FAM and VIC/HEX detection channels.
  • Provides precise results through the TaqMan probe-based allelic discrimination method.
  • CE-IVD
  • Real-time PCR
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