ICP/MS/MS - Metallomics

Vlastnosti

Co je to metalomika? Více informací zde.

Reference: Metallomics Center of the Americas

• Very sensitive - 1000 times or better than organic mass.
• High ionisation efficiency - good for P, S, Se compounds.
• Compound independent calibration - easy and quick quantification.
• Multi-element capabilities > 30 elements simultaneously
• Wide dynamic range = ppm~ppb~ppt simultaneously
• Isotope ratio measurement - Isotope Dilution, Metal tracer.
• Easily interfaced to multiple separation techniques - On-line detector.
• It is recognized that metals play an important roles in proteomics processes as such:
  - About 30% of all proteins may bind metal ions
  - There are many proteins known to bind Ca, Mg, Fe, Zn or Ni ions or chromogenic groups like heme or chlorophyll which bind metal ions.