
The geneMAP™ MTHFR C677T Mutation Detection Kit is a rapid and accurate real-time PCR assay for the detection of the 677C>T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene. This mutation is associated with reduced enzyme activity leading to hyperhomocysteinemia and toxic side effects of methotrexate treatment. The kit is designed to identify patients predisposed to develop cardiovascular diseases or intolerance to methotrexate.
Size: 50 tests
Features
- Easy to use with a ready-to-use reaction mix.
- Delivers accurate results, including Homozygous and Heterozygous controls.
- Compatible with dual-color real-time PCR instruments using FAM and VIC/HEX detection channels.
- Provides precise results through the TaqMan probe-based allelic discrimination method.
- CE-IVD
- Real-time PCR
Related Products

geneMAP™ Thrombophilia Panel (FII, FVL, MTHFR677, MTHFR1298)
The geneMAP™ Thrombophilia Panel (4) Kit is a rapid and accurate real-...

geneMAP™ Celiac (DQ2, DQ8, DR4) Detection Kit
The geneMAP™ Celiac (DQ2, DQ8, DR4) Detection Kit can detect HLA-DQ2,...

geneMAP™ SMN1 Exon7/8 Screening Kit
The geneMAP™ SMN1 Exon 7/8 Deletion Screening Kit is an in vitro nucle...

geneMAP™ FMF 11 Mutation Detection Kit
The geneMAP™ FMF 11 Mutation Detection Kit is a reliable real-time PCR...

geneMAP™ FMF 5 Mutation Detection Kit
The geneMAP™ FMF 5 Mutation Detection Kit is a simple and efficient re...

geneMAP™ HLA-B*57:01 Detection Kit
The geneMAP™ HLA-B*57:01 Detection Kit is a rapid and accurate real-ti...

geneMAP™ HLA-B*51 Detection Kit
The HLA-B*51 allele, a class I human leukocyte antigen (HLA) molecule,...

geneMAP™ HLA-B*27 Detection Kit
The geneMAP™ HLA-B*27 Detection Kit, discriminates the presence or abs...

geneMAP™ Thrombophilia Panel (FII, FVL, C677 & A1298)
Size: 50 tests

geneMAP™ FV Leiden Mutation Detection Kit
The geneMAP™ FV Leiden Mutation Detection Kit is a rapid and accurate...

geneMAP™ FII Mutation Detection Kit
The geneMAP™ FII Mutation Detection Kit is a rapid and accurate, real-...

geneMAP™ MTHFR A1298C Mutation Detection Kit
geneMAP™ MTHFR A1298C Mutation Detection Kit is a fast and accurate re...

geneMAP™ PAI-1 4G/5G Mutation Detection Kit
The geneMAP™ PAI-1 4G/5G Mutation Detection Kit is a fast and accurate...

geneMAP™ FXIII Mutation Detection Kit
The geneMAP™ FXIII Mutation Detection Kit is a fast and accurate real-...

geneMAP™ DPYD Mutations Detection Kit
Dihydropyrimidine dehydrogenase (DPD) is an enzyme encoded by the DPYD...