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geneMAP™ MGMT Methylation Analysis Kit

Genmark

The geneMAP™ MGMT Methylation Analysis Kit is a methylation-specific Realtime PCR (MSP) test designed to detect and quan- tification O (6) -methylguanine-DNA methyltransferase (MGMT) promoter hypermethylation status in genomic DNA of glioblas- toma multiform (GBM) tumors. MGMT promoter methylation has been shown to lead to increased sensitivity to alkylating agents such as temozolomide and to have a favorable prognostic significance.

Size: 50 tests

Features

  • Quantitative detection of MGMT hypermethylation.
  • Specially designed for methylation analysis by routine RT-qPCR.
  • Easy to use Multiplex real-time PCR technology.
  • Calibrator and Positive Control allow results to be obtained as a percentage.
  • CE-IVD
  • Real-time PCR
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